MECHANISMS OF REGENERATIVE MEDICINE USING PRIMARY NULL NEURAL STEM CELLS.

AUTHOR – Y. О. KOROLOV, CANDIDATE OF LAW SCIENCE, DOCTORAL STUDENT OF THE DEPARTMENT OF LAW, PRIVATE HIGHER EDUCATIONAL ESTABLISHMENT, EUROPEAN UNIVERSITY, SPACE INTERNATIONAL COMPANY, INVIDUAL BUSINESS Y.O.KOROLOV. EMAIL: SOAHCIT@GMAIL.COM

ORCID ID: 0009-0000-2037-3419

BEST CITATION – Y. О. KOROLOV, MECHANISMS OF REGENERATIVE MEDICINE USING PRIMARY NULL NEURAL STEM CELLS, ILE MULTIDISCIPLINARY JOURNAL, 4 (1) OF 2025, PG. 622-627, APIS – 3920-0007 | ISSN – 2583-7230

Introduction.

The potential use of neural stem cells (NSCs) in human clinical therapy has led to rapid progress in research into the properties of NSCs, their innate and directed differentiation potential, and induced reprogramming of differentiated cells. Cells revert to a preferential NSC-like state.

The purpose of this review is to provide an overview of our current operational definitions of NSCs, the growing understanding of extrinsic and intrinsic mechanisms, including heritable but reversible epigenetic modifications of cells, and to highlight pioneering efforts to reprogram cells to generate patient-specific stem cells for cell replacement therapy.

This is compared to the current practical procedures for the application of NSCs, as well as to the current state of the art of human regenerative medicine based on NSCs. Both of these lay the groundwork for translating recent findings into innovative clinical applications with the hope of improving the safety, efficacy, and ethical acceptability of NSC-based therapies in the near future.

Keywords: Industrystem, cellsgene,  therapycellular, therapyregenerative, medicine.